Genetics of Parkinson's disease and biochemical studies of implicated gene products: Commentary
β Scribed by Peter T Lansbury Jr; Alexis Brice
- Book ID
- 114309421
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 322 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0955-0674
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## Abstract Over the past decade, major progress has been achieved in the identification of genes associated with Parkinson's disease (PD) and parkinsonism. Five genes have now been shown conclusively to play a role in PD susceptibility. Mutations in three of these genes, __PRKN__, __PINK1,__ and _
## Abstract Parkinson's disease (PD) has long been regarded as having a hereditary component. However, three recent twin studies have been interpreted as excluding any significant genetic component in the etiology of PD. In this article, we reexamine these twin studies and argue that such a conclus