Acute promyelocytic leukemia is characterized by the reciprocal translocation of chromosomes 15 and 17. All-trans retinoic acid (ATRA) efficiently induces differentiation of the abnormal promyelocytes. In this study, we had used ATRA as the primary induction therapy for 17 newly diagnosed patients,
Genetics of APL and the molecular basis of retinoic acid treatment
β Scribed by Tullia Casini; Francesco Grignani; Pier G. Pelicci
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- French
- Weight
- 51 KB
- Volume
- 70
- Category
- Article
- ISSN
- 0020-7136
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