Genetics in rheumatoid arthritis

✍ Scribed by Tom W.J. Huizinga

• Book ID: 114411269
• Publisher: Elsevier Science
• Year: 2003
• Tongue: English
• Weight: 132 KB
• Volume: 17
• Category: Article
• ISSN: 1521-6942
• DOI: 10.1016/s1521-6942(03)00040-8

✦ Synopsis

This chapter reviews the latest original research on the genetics of rheumatoid arthritis (RA), with a focus on its relevance for the clinical rheumatologist. The following questions will be dealt with in order to appreciate the recent progress in this field. * Why is a knowledge of genetics useful for an understanding of the pathogenesis of RA? * Is a knowledge of genetic risk factors relevant for day-to-day clinical practice? * What methods are used for identifying genetic risk factors? * Which genetic regions have been identified in susceptibility to RA? * What risk factors have been identified? * What are the future prospects and research agenda?