𝔖 Bobbio Scriptorium
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Genetics: Genes linked to colon cancer take sides


Book ID
112202255
Publisher
Society for Science & the Public
Year
2009
Tongue
English
Weight
41 KB
Volume
164
Category
Article
ISSN
0036-8423

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## Abstract Hereditary nonpolyposis colon cancer (HNPCC) is associated with malfunction of postreplicative mismatch repair (MMR). While a majority of HNPCC‐associated mutations in the MMR genes __MLH1, MSH2,__ or __MSH6__ genes cause truncationsβ€”and thus loss of functionβ€”of the respective polypepti