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Genetics and pharmacogenetics of the leukotriene pathway

โœ Scribed by Tantisira, Kelan G.; Drazen, Jeffrey M.


Book ID
119282428
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
279 KB
Volume
124
Category
Article
ISSN
1097-6825

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Genetic contribution of the leukotriene
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We evaluated the genetic contribution of the leukotriene (LT) pathway to risk of coronary artery disease (CAD) in 4,512 Caucasian and African American subjects ascertained through elective cardiac evaluation. Of the three previously associated variants, the shorter โ€œ3โ€ and โ€œ4โ€ alleles of a promoter