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Genetics and molecular profiling of multiple myeloma: Novel tools for clinical management?

✍ Scribed by Pierfrancesco Tassone; Pierosandro Tagliaferri; Marco Rossi; Marco Gaspari; Rosa Terracciano; Salvatore Venuta

Book ID
116429011
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
187 KB
Volume
42
Category
Article
ISSN
0959-8049

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Multiple myeloma is a plasma cell malignancy characterized by complex heterogenous cytogenetic abnormalities that accounts for 1.4% of all cancers, and approximately 10% of hematologic malignancies. The clinical manifestations of multiple myeloma include lytic bone lesions, cytopenia, hypercalcemia,