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Genetics and Genetic Testing in Hemolytic Uremic Syndrome/Thrombotic Thrombocytopenic Purpura

โœ Scribed by Noris, Marina; Remuzzi, Giuseppe


Book ID
121888419
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
379 KB
Volume
30
Category
Article
ISSN
0270-9295

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Thrombotic thrombocytopenic purpura-hemolytic uremic syndrome (TTP-HUS) is a clinical syndrome defined by the presence of thrombocytopenia and microangiopathic hemolytic anemia without a clinically apparent etiology. Patients may also have multiple other symptoms and signs including neurologic and r

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A retrospective analysis was made of 14 consecutive adults with hemolytic uremic syndromeithrombotic thrombocytopenic purpura (HUSiTTP) who were treated with plasma exchange (PE). In six patients the disease was primary, whilst in eight HUSiTTP was considered secondary to an associated condition. Th