Genetically engineered CNS progenitor cells and primary neuroepithelial cells are growth restricted and differentiate following transplantation into the fetal rat brain

Scattered primary and conditionally immo

Scattered primary and conditionally immortalized neuroepithelial cells transplanted into the embryonic rat brain differentiate into neurons and glial cells

✍ Lorenzo Magrassi; Stefano Pezzotta; Giorgio Butti; Luciano Conti; Stefano Govoni 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 646 KB

Insights into the molecular and cellular mechanisms underlying CNS development have been obtained by placing immature CNS cells ectopically into the brain. Our previous short-term survival experiments demonstrated that when immature cells were transplanted into the developing Nervous System the majo