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Genetically distinct and clinically relevant subtypes of glioblastoma defined by array-based comparative genomic hybridization (array-CGH)

✍ Scribed by Andrey Korshunov; Regina Sycheva; Andrey Golanov

Book ID
106073366
Publisher
Springer-Verlag
Year
2006
Tongue
English
Weight
438 KB
Volume
111
Category
Article
ISSN
0001-6322

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## Abstract We have undertaken an extensive high‐resolution analysis of loss of heterozygosity (LOH) in 30 high grade gliomas using the Affymetrix 100K SNP mapping array. Only 70% of LOH events were accompanied by a copy number loss (CNA~loss~), and of the other 30%, the distal region of 17p prefer