Genetically determined differences in liver alcohol dehydrogenase activity in male rats
β Scribed by David W. Crabb; Ting-Kai Li
- Publisher
- Springer
- Year
- 1985
- Tongue
- English
- Weight
- 497 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0006-2928
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The hepatic lobular localization of alcohol dehydrogenase was determined in male, female and castrated male rats. Alcohol dehydrogenase immunoreactive protein and activity were increased in female and castrated rats as compared to normal male rats. By immunohistochemistry, alcohol dehydrogenase prot
## Abstract Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH), which are most abundant in the liver, are the main enzymes involved in ethanol metabolism in humans. Genderβrelated differences in total liver ADH and ALDH activity among different animal species have been observed in many s