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Genetic Variation Near the Hepatocyte Nuclear Factor-4 Gene Predicts Susceptibility to Type 2 Diabetes

✍ Scribed by Silander, K.; Mohlke, K. L.; Scott, L. J.; Peck, E. C.; Hollstein, P.; Skol, A. D.; Jackson, A. U.; Deloukas, P.; Hunt, S.; Stavrides, G.

Book ID: 115481586
Publisher: American Diabetes Association
Year: 2004
Tongue: English
Weight: 274 KB
Volume: 53
Category: Article
ISSN: 0012-1797
DOI: 10.2337/diabetes.53.4.1141

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## Communicated by Haig Kazazian Mutations in the homeodomain-containing transcription factor hepatocyte nuclear factor-1 β β (HNF-1 β β ) are known to cause a rare subtype of maturity-onset diabetes of the young (MODY5), which is associated with early-onset progressive non-diabetic renal dysfunct