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Genetic variation near the GDF5 gene is associated with hip geometry

✍ Scribed by M.C. Castano Betancourt; F. Rivadeneira; E. Waarsing; S. Bierma-Zeinstra; A. Hofman; H. Weinans; A. Uitterlinden; J. Van Meurs

Book ID: 116324466
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 56 KB
Volume: 48
Category: Article
ISSN: 8756-3282
DOI: 10.1016/j.bone.2011.03.339

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## Abstract ## Objective The ANP32A gene encodes a tumor suppressor molecule that plays a regulatory role in apoptosis and interferes with canonical Wnt signaling in vitro. We undertook this study to test whether genetic variation at ANP32A was associated with osteoarthritis (OA) in women. ## Met