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Genetic variation in transforming growth factor-beta1 gene associated with increased risk of esophageal squamous cell carcinoma

✍ Scribed by Y.-S. Wei; Q.-Q. Xu; C.-F. Wang; Y. Pan; F. Liang; X.-K. Long

Book ID
110892659
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
111 KB
Volume
70
Category
Article
ISSN
0001-2815

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## Abstract Transforming growth factor‐β (TGF‐β) regulates cell growth inhibition, and inactivation of the TGF‐β signaling pathway contributes to tumor development. In our previous study, altered expression of TGF‐β, TGF‐β‐specific receptors and Smad4 was shown to correlate with tumor progression i