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Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

โœ Scribed by Romeo, Stefano (author);Kozlitina, Julia (author);Xing, Chao (author);Pertsemlidis, Alexander (author);Cox, David (author);Pennacchio, Len A. (author);Boerwinkle, Eric (author);Cohen, Jonathan C. (author);Hobbs, Helen H. (author)

Book ID
109914347
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
491 KB
Volume
40
Category
Article
ISSN
1061-4036

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Genetic variation in PNPLA3 confers susc
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โœ Romeo, Stefano (author);Kozlitina, Julia (author);Xing, Chao (author);Pertsemlid ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› Nature Publishing Group ๐ŸŒ English โš– 491 KB

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Genome-wide association studies identified single-nucleotide polymorphisms (SNPs) that are associated with increased hepatic fat or elevated liver enzymes, presumably reflecting nonalcoholic fatty liver disease (NAFLD). To investigate whether these SNPs are associated with histological severity of N