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Genetic Variation in IL28B: Impact on Drug Development for Chronic Hepatitis C Infection

โœ Scribed by Clark, P J; Thompson, A J V; McHutchison, J G

Book ID
109846075
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
117 KB
Volume
88
Category
Article
ISSN
0009-9236

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## Abstract It has been reported that genetic polymorphisms near the __IL28B__ gene or amino acid substitutions in hepatitis C virus (HCV) core protein are associated with the clinical outcome of peginterferon (PEGโ€IFN) and ribavirin combination therapy. The impact of these factors on the pure sens