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Genetic variation in DLG5 is associated with inflammatory bowel disease

✍ Scribed by Stoll, Monika; Corneliussen, Brit; Costello, Christine M; Waetzig, Georg H; Mellgard, Bjorn; Koch, W Andreas; Rosenstiel, Philip; Albrecht, Mario; Croucher, Peter J P; Seegert, Dirk

Book ID: 109918993
Publisher: Nature Publishing Group
Year: 2004
Tongue: English
Weight: 184 KB
Volume: 36
Category: Article
ISSN: 1061-4036
DOI: 10.1038/ng1345

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Background: Variants in the DLG5 gene have been associated with inflammatory bowel disease (IBD) in samples from some, but not all populations. In particular, 2 nonsynonymous single-nucleotide polymorphisms (SNPs), R30Q (rs1248696) and P1371Q (rs2289310), have been associated with an increased risk