Genetic variation in alkaline phosphatase of the house mouse (Mus musculus) with emphasis on a manganese-requiring isozyme
✍ Scribed by Frank H. Wilcox; Lisa Hirschhorn; Benjamin A. Taylor; James E. Womack; Thomas H. Roderick
- Publisher
- Springer
- Year
- 1979
- Tongue
- English
- Weight
- 730 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0006-2928
No coin nor oath required. For personal study only.
✦ Synopsis
Genetic variation among inbred strains is described for electrophoretic migration of alkaline phosphatase from intestine, kidney, blood plasma, and three isozymes of liver. A manganese-requiring isozyme of liver and kidney unaffected by neuraminidase is described, and the locus controlling variation in this isozyme is designated Akp-1. Data from recombinant inbred strains place the locus on chromosome 1 az a distance of 3.6 +_ 2.9 cM from the Mls locus on the side distal to the centromere. Test-cross data show the following gene order and recombination percentages.