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Genetic variants ofp27andp21as predictors for risk of second primary malignancy in patients with index squamous cell carcinoma of head and neck

✍ Scribed by Zhongqiu Wang; Erich M Sturgis; Fenghua Zhang; Dapeng Lei; Zhensheng Liu; Li Xu; Xicheng Song; Qingyi Wei; Guojun Li


Book ID
115020462
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
196 KB
Volume
11
Category
Article
ISSN
1476-4598

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p73 G4C14-to-A4T14 polymorphism and risk
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## Abstract P73 plays an important role in modulating cell‐cycle control, inducing apoptosis, and inhibiting cell growth. A novel noncoding __p73__ G4C14‐to‐A4T14 exon 2 polymorphism was associated with risk of squamous cell carcinoma of the head and neck (SCCHN). We hypothesized that __p73__ G4C14