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Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus

✍ Scribed by Graham, Robert R; Cotsapas, Chris; Davies, Leela; Hackett, Rachel; Lessard, Christopher J; Leon, Joanlise M; Burtt, Noel P; Guiducci, Candace; Parkin, Melissa; Gates, Casey

Book ID: 109914237
Publisher: Nature Publishing Group
Year: 2008
Tongue: English
Weight: 265 KB
Volume: 40
Category: Article
ISSN: 1061-4036
DOI: 10.1038/ng.200

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## Abstract ## Objective Both genetic and epigenetic factors play an important role in the pathogenesis of lupus. The aim of this study was to examine methyl‐CpG–binding protein 2 gene (__MECP2__) polymorphisms in a large cohort of patients with lupus and control subjects, and to determine the fun