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Genetic variants in trinucleotide repeat-containing 9 (TNRC9) are associated with risk of estrogen receptor positive breast cancer in a Chinese population

✍ Scribed by Jie Liang; Peizhan Chen; Zhibin Hu; Hao Shen; Furu Wang; Lu Chen; Mian Li; Jinhai Tang; Hui Wang; Hongbing Shen

Publisher: Springer US
Year: 2010
Tongue: English
Weight: 165 KB
Volume: 124
Category: Article
ISSN: 0167-6806
DOI: 10.1007/s10549-010-0809-z

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## Abstract Interleukin 1β (IL‐1β) is a multifunctional cytokine that upregulates the inflammatory response, and participates in carcinogenesis, malignant transformation, tumor growth, invasion and metastasis. Two potentially functional polymorphisms (T‐31C and C‐511T) in the __IL‐1__β gene promote