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Genetic variants in theSOX6gene are associated with bone mineral density in both Caucasian and Chinese populations

โœ Scribed by T.-L. Yang; Y. Guo; Y.-J. Liu; H. Shen; Y.-Z. Liu; S.-F. Lei; J. Li; Q. Tian; H.-W. Deng


Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
175 KB
Volume
23
Category
Article
ISSN
0937-941X

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Rare coding variants in ALPL are associa
โœ Carrie M Nielson; Joseph M Zmuda; Amy S Carlos; Wendy J Wagoner; Emily A Larson; ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› American Society for Bone and Mineral Research ๐ŸŒ English โš– 415 KB

## Abstract Alkaline phosphatase (ALP) plays an essential role in the regulation of tissue mineralization, and its activity is highly heritable. Guided by genetic associations discovered in a murine model, we hypothesized a role for rare coding variants in determining serum ALP level and bone miner