✦ LIBER ✦

Genetic variants in the cell cycle control pathways contribute to early onset colorectal cancer in Lynch syndrome

✍ Scribed by Jinyun Chen; Carol J. Etzel; Christopher I. Amos; Qing Zhang; Nancy Viscofsky; Noralane M. Lindor; Patrick M. Lynch; Marsha L. Frazier

Book ID: 106382933
Publisher: Springer Netherlands
Year: 2009
Tongue: English
Weight: 280 KB
Volume: 20
Category: Article
ISSN: 0957-5243
DOI: 10.1007/s10552-009-9416-x

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Genetic variants in cell cycle control p

Genetic variants in cell cycle control pathway confer susceptibility to bladder cancer

✍ Yuanqing Ye; Hushan Yang; H. Barton Grossman; Colin Dinney; Xifeng Wu; Jian Gu 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 155 KB

## Abstract ## BACKGROUND Cell cycle checkpoint regulation is crucial for the prevention of carcinogenesis in mammalian cells. ## METHODS To test the hypothesis that common sequence variants in the cell cycle control pathway may affect bladder cancer susceptibility, the effects of a panel of 10

The degradation of cell cycle regulators

The degradation of cell cycle regulators by SKP2/CKS1 ubiquitin ligase is genetically controlled in rodent liver cancer and contributes to determine the susceptibility to the disease

✍ Diego F. Calvisi; Federico Pinna; Sara Ladu; Maria R. Muroni; Maddalena Frau; Il 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 French ⚖ 560 KB

## Abstract Previous work showed a genetic control of cell cycle deregulation during hepatocarcinogenesis. We now evaluated in preneoplastic lesions, dysplastic nodules and hepatocellular carcinoma (HCC), chemically induced in genetically susceptible F344 and resistant Brown Norway (BN) rats, the r