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Genetic Variants in Apoptosis and Immunoregulation-Related Genes Are Associated with Risk of Chronic Lymphocytic Leukemia

✍ Scribed by Enjuanes, A.; Benavente, Y.; Bosch, F.; Martin-Guerrero, I.; Colomer, D.; Perez-Alvarez, S.; Reina, O.; Ardanaz, M. T.; Jares, P.; Garcia-Orad, A.; Pujana, M. A.; Montserrat, E.; de Sanjose, S.; Campo, E.


Book ID
126254480
Publisher
American Association for Cancer Research
Year
2008
Tongue
English
Weight
383 KB
Volume
68
Category
Article
ISSN
0008-5472

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B chronic lymphocytic leukemia (B-CLL) is a heterogeneous disease. The different morphological variants of leukemic B cells appear to define different clinical groups of patients. Several abnormalities have been found in T lymphocytes and natural killer (NK) cells from B-CLL patients. We have invest