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Genetic variant in KIAA0319 , but not in DYX1C1 , is associated with risk of dyslexia: An integrated meta-analysis

✍ Scribed by Zou, Li; Chen, Wei; Shao, Shanshan; Sun, Zhao; Zhong, Rong; Shi, Junxin; Miao, Xiaoping; Song, Ranran

Book ID: 118751230
Publisher: John Wiley and Sons
Year: 2012
Tongue: English
Weight: 159 KB
Volume: 159B
Category: Article
ISSN: 1552-4841
DOI: 10.1002/ajmg.b.32102

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## Abstract Myeloperoxidase (MPO), an enzyme derived from neutrophils, metabolically activates a wide range of carcinogens, whereas glutathione __S__‐transferase M1 (GSTM1) detoxifies various electrophilic metabolites. A ‐463G→A polymorphism in the promoter region of the __MPO__ gene diminishes the