Genetic testing in Huntington's disease
β Scribed by William C. Koller; Joyce Davenport
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 249 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0364-5134
No coin nor oath required. For personal study only.
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## Abstract Twelve Italian families with Huntington disease were tested with 10 probes known to be linked to the disease locus and able to detect polymorphisms at the following loci on chromosome 4: D4S10, D4S127, D4S95, D4S43, D4S115, D4S111, D4S90. The results confirmed the applicability of the l
The psychological impact of DNA predictive testing on asymptomatic individuals at risk for Huntington disease (HD) has received considerable attention since the advent of the procedure in 1993. This study examined the impact of such testing on families from the families' perspective. Individuals asy