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Genetic testing for malignant hyperthermia

✍ Scribed by Jane Halsall; Rachel Robinson


Book ID
113509583
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
280 KB
Volume
15
Category
Article
ISSN
0953-7112

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The genetics of malignant hyperthermia:
✍ McPherson, Elspeth ;Taylor, Claude A. ;Opitz, John M. πŸ“‚ Article πŸ“… 1982 πŸ› John Wiley and Sons 🌐 English βš– 756 KB

## Abstract Study of phenotype and familial distribution of malignant hyperthermia (MH) suggests heterogeneity with MH possibly being a symptom of several disorders. Review of all reported family studies supports the concept of heterogeneity with autosomal dominant inheritance in about one‐half of

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Malignant hyperthermia (MH) is a potentially life-threatening event in response to anesthetic triggering agents, with symptoms of sustained uncontrolled skeletal muscle calcium homeostasis resulting in organ and systemic failure. Susceptibility to MH, an autosomal dominant trait, may be associated w