Genetic testing for malignant hyperthermia
β Scribed by Jane Halsall; Rachel Robinson
- Book ID
- 113509583
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 280 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0953-7112
No coin nor oath required. For personal study only.
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## Abstract Study of phenotype and familial distribution of malignant hyperthermia (MH) suggests heterogeneity with MH possibly being a symptom of several disorders. Review of all reported family studies supports the concept of heterogeneity with autosomal dominant inheritance in about oneβhalf of
Malignant hyperthermia (MH) is a potentially life-threatening event in response to anesthetic triggering agents, with symptoms of sustained uncontrolled skeletal muscle calcium homeostasis resulting in organ and systemic failure. Susceptibility to MH, an autosomal dominant trait, may be associated w