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Genetic Susceptibility to Head and Neck Squamous Cell Carcinoma

✍ Scribed by Lacko, Martin; Braakhuis, Boudewijn J.M.; Sturgis, Erich M.; Boedeker, Carsten C.; Suárez, Carlos; Rinaldo, Alessandra; Ferlito, Alfio; Takes, Robert P.

Book ID
122559401
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
389 KB
Volume
89
Category
Article
ISSN
0360-3016

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Genetic polymorphisms of drug-metabolizing enzymes and susceptibility to head-and-neck squamous-cell carcinoma
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We have investigated the association between the polymorphisms of drug-metabolizing enzymes and susceptibility to head-and-neck squamous-cell carcinoma (HNSCC). PCRbased analysis was performed on 145 Japanese patients and 164 healthy Japanese controls to determine genotypes of polymorphisms in CYP1A