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Genetic susceptibility to etoposide-induced chromosome aberration formation and sister-chromatid exchanges (SCEs) in cultured human lymphocytes

โœ Scribed by T. Ohe; M. Tokuda; K. Nakamiti; T. Abe


Book ID
113252284
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
169 KB
Volume
253
Category
Article
ISSN
0165-1161

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Peripheral blood lymphocytes from three patients with Down syndrome (DS; trisomy 21; aged 5-6 years) and three age-matched control children were studied for the induction of chromosomal aberrations and sister chromatid exchanges (SCEs). Cells in G0 were exposed to bleomycin (20-100 micrograms/ml) fo