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Genetic susceptibility to chronic Chagas disease: An overview of single nucleotide polymorphisms of cytokine genes

✍ Scribed by Romero H.T. Vasconcelos; Silvia M.L. Montenegro; Elisa A.N. Azevedo; Yara M. Gomes; Clarice N.L. Morais

Book ID
116400657
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
202 KB
Volume
59
Category
Article
ISSN
1043-4666

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## Abstract ## Objective Gene–gene interaction, or epistasis, is considered a ubiquitous component of complex human diseases such as systemic sclerosis (SSc). Epistasis is difficult to model by traditional parametric approaches; therefore, nonparametric computational algorithms, such as multifacto