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Genetic support for a critical role EGF receptor signaling in intestinal neoplasia in ApcMin mice

✍ Scribed by Robert J. Coffey Jr; Reade Roberts; Stephen H. Settle; Robert Whitehead; Kay Washington; David Threadgill


Book ID
119428953
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
189 KB
Volume
120
Category
Article
ISSN
0016-5085

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## Abstract Emerging evidence supports an inhibitory role for vitamin D in colorectal carcinogenesis; however, the mechanism remains unclear. The adenomatous polyposis coli (APC)/β‐catenin pathway plays a critical role in colorectal carcinogenesis. The purpose of our study is to explore the interac