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Genetic studies on the β subunit of Escherichia coil RNA polymerase

✍ Scribed by Nene, Vishvanath ;Glass, Robert E.

Publisher
Springer
Year
1984
Tongue
English
Weight
31 KB
Volume
196
Category
Article
ISSN
0026-8925

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We have isolated a set of strains that synthesise 331 potential variants of E. coli DNA-dependent RNA polymerase making use of nonsense suppression of amber mutations in the beta structural gene; rpoB. Translational mapping, together with the effect of known amino acid substitutions, has allowed us