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Genetic sexing inDrosophila melanogasterusing the alcohol dehydrogenase locus and a Y-linked translocation

โœ Scribed by A. S. Robinson; C. Heemert


Publisher
Springer
Year
1981
Tongue
English
Weight
154 KB
Volume
59
Category
Article
ISSN
0040-5752

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โœฆ Synopsis


By incorporating ethanol (4% v/v) into the larval rearing medium of a specially constructed Drosophila melanogaster strain it was possible to produce only male adults; the female larvae died.In this strain, the male determining chromosome was linked with a positive Alcohol dehydrogenase (ADH) allele by a translocation. The females were homozygous for the null allele and hence sensitive to ethanol.This genetic sexing method is discussed in relation to its use in the genetic control of insects.


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Electrophoretic and activity variants for a liver aldehyde reductase (AHR-A2) among strains of Mus musculus have been used in genetic analyses to demonstrate close linkage between the locus encoding this enzyme (designated Ahr-1) and the alcohol dehydrogenase gene complex on chromosome 3. No recombi