𝔖 Bobbio Scriptorium
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Genetic screening for progressive retinal atrophy in the Australian population of Irish Setters

✍ Scribed by P. MAROUDAS; AI JOBLING; RC AUGUSTEYN


Book ID
111408708
Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
29 KB
Volume
78
Category
Article
ISSN
0005-0423

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The cyclic guanosine monophosphate specific phosphodiesterase (cGMP‐specific PDE) is a key enzyme in the phototransduction cascade of the vertebrate retina. This enzyme consists of two catalytic Ξ± and Ξ² subunits, two identical inhibitory Ξ³ subunits as well as a Ξ΄ subunit. Mutations in __PDE6A__ and