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Genetic screening for familial hypercholesterolemia in french canadians

✍ Scribed by A. Chamberland; J. Lavigne; J. Davignon; A. Minnich


Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
120 KB
Volume
27
Category
Article
ISSN
0009-9120

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πŸ“œ SIMILAR VOLUMES


Molecular genetic evidence for a founder
✍ Christine BΓ©tard; A. M. Kessling; M. Roy; A. Chamberland; S. Lussier-Cacan; J. D πŸ“‚ Article πŸ“… 1992 πŸ› Springer 🌐 English βš– 786 KB

Familial hypercholesterolemia (FH), at a prevalence of about 1 in 200 in the French-Canadian population, is caused by a 10-kb deletion in the low-density lipoprotein (LDL) receptor gene in 60% of French-Canadian FH heterozygotes. We genotyped 159 FH patients who carry this common mutation and 221 he