Genetic predisposition for the development of head and neck cancer
- Book ID
- 117610271
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 238 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0901-5027
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## Abstract ## __Background.__ Based on the International Classification of Functioning (ICF)βDisability and Health, participants from different professional and cultural backgrounds were invited to achieve consensus on a first version of ICF Core Set for head and neck cancer (HNC). It was designe
Significant interindividual variations in health outcome may be caused by the inheritance of variant polymorphic genes, such as CYP2D6 and CYP2E1 for activation, and GSTM1 and GSTT1 for detoxification of chemicals. However, mechanistic studies linking the inheritance of predisposing genes with genot
## Abstract ## BACKGROUND: Secondary primary cancers (SPCs), a major cause of morbidity and mortality in head and neck cancers (HNCs), are commonly associated with field cancerization. We comprehensively evaluated 23 germline sequence variants (from published literature) in 17 genes from 7 biologi