Genetic prediction in Huntington's disea
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V. Peter Misra; Michael Baraitser; Dr. A. E. Harding
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Article
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1988
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John Wiley and Sons
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English
โ 242 KB
The major factor limiting use of the polymorphic DNA sequence D4S 10, genetically linked to the Huntington's disease (HD) locus, in clinical practice is the fragmented nature of HD families. A population survey in South Wales suggested that genetic prediction would only be possible in 15% of adults