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Genetic polymorphisms of tobacco- and alcohol-related metabolizing enzymes and the risk of hepatocellular carcinoma

โœ Scribed by Masahiro Munaka; Kiyotaka Kohshi; Toshihiro Kawamoto; Shin Takasawa; Naoki Nagata; Hideaki Itoh; Susumu Oda; Takahiko Katoh


Book ID
106123262
Publisher
Springer-Verlag
Year
2003
Tongue
English
Weight
187 KB
Volume
129
Category
Article
ISSN
1432-1335

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Both genetic and environmental factors are involved in the development of cancer. Oral cavity cancer has been reported to be epidemiologically associated with tobacco and alcohol consumption. We examined genetic polymorphisms of the glutathione-S-transferase (GST) M1/T1, cytochrome P-450 (CYP) 1A1/2