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Genetic polymorphisms of enzymes involved in xenobiotic metabolism among Greenlandic Inuit

✍ Scribed by M. Ghisari; H. Eiberg; E.C. Bonefeld-Jørgensen

Book ID
116924804
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
77 KB
Volume
205
Category
Article
ISSN
0378-4274

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Polymorphisms in xenobiotic metabolizing enzymes have been implicated in inter-individual and inter-ethnic differences in cancer susceptibilty. Several studies have indicated an association between variant alleles of the human CYP1A1, CYP2E1 and GSTM1 genes and lung cancer. Activity of microsomal ep