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Genetic polymorphisms of CYP2D6 oxidation in patients with systemic sclerosis

✍ Scribed by Jadwiga Skrętkowicz; Malgorzata Baranska; Mariola Rychlik-Sych


Publisher
Springer
Year
2009
Tongue
English
Weight
126 KB
Volume
65
Category
Article
ISSN
0031-6970

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✍ V. Planté-Bordeneuve; O. Bandmann; G. Wenning; N. P. Quinn; S. E. Daniel; Prof. 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 200 KB

Molecular genetic studies of the cytochrome P450 system enzyme CYP2D6, which hydroxylates debrisoquine, have indicated an excess of mutant alleles in large series of patients with Parkinson's disease (PD) when compared with controls. We have investigated C YP2D6 polymorphism in 91 patients with mult