Genetic Polymorphisms in the Catechol Estrogen Metabolism Pathway and Breast Cancer Risk
β Scribed by Reding, K. W.; Weiss, N. S.; Chen, C.; Li, C. I.; Carlson, C. S.; Wilkerson, H.-W.; Farin, F. M.; Thummel, K. E.; Daling, J. R.; Malone, K. E.
- Book ID
- 121792117
- Publisher
- American Association for Cancer Research
- Year
- 2009
- Tongue
- English
- Weight
- 174 KB
- Volume
- 18
- Category
- Article
- ISSN
- 1055-9965
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## Abstract Estrogen and its metabolites are believed to play important roles in breast cancer, and its determinants include both genetic and lifestyle factors. The objective of the study is to investigate the association of breast cancer risk in Thailand with genetic polymorphisms in several genes
## Abstract Estrogen has been suggested to trigger breast cancer development via an initiating mechanism involving its metabolite, catechol estrogen (CE). To examine this hypothesis, we carried out a multigenic caseβcontrol study of 469 incident breast cancer patients and 740 healthy controls to de