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Genetic polymorphisms in folate pathway enzymes as a possible marker for predicting the outcome of methotrexate therapy in Japanese patients with rheumatoid arthritis

✍ Scribed by H. Hayashi; C. Fujimaki; T. Daimon; S. Tsuboi; T. Matsuyama; K. Itoh

Book ID: 108849252
Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 108 KB
Volume: 34
Category: Article
ISSN: 0269-4727
DOI: 10.1111/j.1365-2710.2009.01046.x

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## Abstract ## Objective Among patients with rheumatoid arthritis (RA), there is a high degree of interindividual variability in the degree of response to methotrexate (MTX) treatment. This study was undertaken to explore polymorphisms in genes contributing to antiinflammatory adenosine release as