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Genetic polymorphisms and alternative splicing of the hOGG1 gene, that is involved in the repair of 8-hydroxyguanine in damaged DNA

✍ Scribed by Kohno, Takashi; Shinmura, Kazuya; Tosaka, Masahiko; Tani, Masachika; Kim, Su-Ryang; Sugimura, Haruhiko; Nohmi, Takehiko; Kasai, Hiroshi; Yokota, Jun

Book ID: 110061374
Publisher: Nature Publishing Group
Year: 1998
Tongue: English
Weight: 389 KB
Volume: 16
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1201872

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## Abstract ## BACKGROUND. Tobacco smoke contains numerous carcinogens that cause DNA damage, including oxidative lesions that are removed effectively by the base‐excision repair (BER) pathway, in which adenosine diphosphate ribosyl transferase (ADPRT), x‐ray repair cross‐complementing 1 (XRCC1),