Genetic polymorphism of the B subunit of coagulation factor XIII in Libyans: Occurrence of a fourth common allele, FXIIIB*6

✍ Scribed by Sebetan, IsmailM. ;Azadeh, Bahram

• Publisher: Springer-Verlag
• Year: 1989
• Tongue: English
• Weight: 380 KB
• Volume: 103
• Category: Article
• ISSN: 1437-1596
• DOI: 10.1007/bf00187566

✦ Synopsis

FXIIIB phenotypes were determined in neuraminidase-pretreated serum samples by using isoelectric focusing in ultrathin-layer polyacrylamide gels containing 1 M urea and subsequent immunoblotting. In a Libyan population sample from Tripoli, (n = 108) nine different phenotypes as products of four common alleles were recognized, with frequencies as follows: FXIIIB*l=0.6574, FXIIIB*2=0.2454, FXIIIB*3 =0.0741 and FXIIIB*6 = 0.0231. It is suggested that FXIIIB*6 is the fourth common allele of the FXIIIB system in this population.