Genetic polymorphism in the second exon of HLA-DRB1 in cervical cancer
✍ Scribed by Yan-yun Li; Gui-fang Yang; Yan-ju Jia; Jun Xing; Yan-ni Li; Wei-ming Zhang
- Book ID
- 107513277
- Publisher
- Springer-Verlag
- Year
- 2010
- Weight
- 935 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1674-5361
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Genetic variation in the equine leucocyte antigen‐__DRB__ (__ELA‐DRB__) second exon was investigated using polymerase chain reaction (PCR) amplification, restriction fragment length polymorphism (RFLP) of PCR products (PCR‐RFLP) and deoxyribonucleic acid (DNA) sequencing. Eight distinct PCR‐RFLP pat
## Abstract Multiple determinants are involved in the progression of human papillomavirus (HPV)‐infected cervical lesion to invasive cancer. Human leukocyte antigen (HLA) polymorphism seems to play a role. This study examined the association between HLA‐DRB1 polymorphism, high‐risk HPV infection, a
## Abstract High‐risk human papillomavirus (hrHPV) infection is the major risk factor for cervical cancer (CxCa). The role of genetic susceptibility in the disease has been suggested, but the existing data lack consistency. We conducted a nested case‐control study on 973 CxCa cases and 1,763 matche