Genetic polymorphism in ethanol metabolism: acetaldehyde contribution to alcohol abuse and alcoholism
β Scribed by Quertemont, E
- Book ID
- 110059785
- Publisher
- Nature Publishing Group
- Year
- 2004
- Tongue
- English
- Weight
- 159 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1359-4184
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π SIMILAR VOLUMES
The physical complications of alcoholism are numerous. 1 ## It is still not clear why some alcoholic patients acquire Different mechanisms are probably involved in different alcocertain organ-specific complications of alcoholism hol-induced end organ diseases, such as those in the liver, whereas
## Abstract Genetic variations increasing blood levels of acetaldehyde, the first metabolite of alcohol, refrain their carriers from drinking alcohol but may also put them at increased risk of cancer because of the mutagenic and carcinogenic effect of acetaldehyde. In a populationβbased study of 30