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Genetic polymorphism at two linked loci, Sod and Est-6, in Drosophila melanogaster

✍ Scribed by Francisco J. Ayala; Evgeniy S. Balakirev; Alberto G. Sáez


Book ID
117521034
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
210 KB
Volume
300
Category
Article
ISSN
0378-1119

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The molecular nature of lethal and semilethal mutations in the Pgd locus of D. melanogaster coding for 6-phosphogluconate dehydrogenase (6PGD) was studied. All the 11 mutations affect the structural gene of the Pgd locus: 3 semilethal mutations resulted in altered 6PGD molecules with decreased catal