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Genetic polymorphism and function of glutathione S-transferases in tumor drug resistance

โœ Scribed by Hui-Wen Lo; Francis Ali-Osman

Book ID
116383574
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
271 KB
Volume
7
Category
Article
ISSN
1471-4892

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We have studied the levels of glutathione S-transferase in drug-resistant and -sensitive human tumor cell lines to examine a possible involvement of glutathione S-transferase (GST) in multidrug resistance mechanisms. No increase in the activity of glutathione S-transferase was detected in myelogenou