## Abstract The recently published comprehensive profiles of genomic alterations in glioma have led to a refinement in our understanding of the molecular events that underlie this cancer. Using stateβofβtheβart genomic tools, several laboratories have created and characterized accurate genetically
β¦ LIBER β¦
Genetic Modeling of Glioma Formation in Mice
β Scribed by Martin Begemann; Gregory N. Fuller; Eric C. Holland
- Book ID
- 111404156
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 624 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1015-6305
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Connexin β£ 3 (Cx46 or Gja3) gene targeted null mice developed lens nuclear cataracts shortly after birth. A large variance in the cataracts was observed in β£ 3 null sibs on a mixed 129SvJae Ο« C57BL/6J F3 background. This suggested that the genetic background might influence the cataract phenotype. T