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Genetic mapping of a second locus predisposing to hereditary non–polyposis colon cancer

✍ Scribed by Lindblom, Annika; Tannergård, Pia; Werelius, Barbro; Nordenskjöld, Magnus

Book ID
109918550
Publisher
Nature Publishing Group
Year
1993
Tongue
English
Weight
447 KB
Volume
5
Category
Article
ISSN
1061-4036

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Sublocalization of a locus at 3p21.3–23
Sublocalization of a locus at 3p21.3–23 predisposing to hereditary nonpolyposis colon cancer
✍ Pia Tannergård; Eugene Zabarovsky; Erik Stanbridge; Magnus Nordenskjöld; Annika 📂 Article 📅 1994 🏛 Springer 🌐 English ⚖ 333 KB

## Hereditary nonpolyposis colon cancer (HNPCC) is a heterogeneous disease caused by at least three different genes on chromosomes 2 and 3, and one or more additional chromosomes. We used 19 dinucleotide markers in order to sublocalize further the 3p locus linked to HNPCC, and to order the markers