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Genetic load in an isolated tribal population of south India

✍ Scribed by Aloke K. Ghosh; Partha P. Majumder


Book ID
104705833
Publisher
Springer
Year
1979
Tongue
English
Weight
318 KB
Volume
51
Category
Article
ISSN
0340-6717

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✦ Synopsis


The Kota of Nilgiri Hills, Tamilnadu, are an isolated tribal population and occupy the lowest stratum in the local social hierarchy. They have developed an economic symbiotic relationship with other tribes of the Nilgiri Hills (e.g., Toda, Kurumba, Badaga), but have almost no social relationship with other communities, such as the Hindu and Muslim, communities, etc. The total population of the Kota is about 1200. Consanguineous marriages are highly favoured in this group. This paper presents data on prenatal, infant and adolescent mortality in relation to the degree of inbreeding. No perceptible difference has been found in mortality figures between consanguineous and non-consanguineous marriages. This may be due to the long history of inbreeding among the Kota. No case of visible congenital malformation has been noticed. The estimates of genetic load as revealed by inbreeding data indicate that genetic load in the Kota is low (perhaps about 1 lethal equivalent per gamete); it is also low in comparison with that in other Indian populations.


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✍ S. Krithika; R. Trivedi; V.K. Kashyap; T.S. Vasulu πŸ“‚ Article πŸ“… 2005 πŸ› Elsevier Science 🌐 English βš– 76 KB

Genetic polymorphisms at 15 tetrameric short tandem repeat (STR) loci were studied in 203 healthy individuals of Adi Pasi population from Arunachal Pradesh, India. All the loci analyzed were highly polymorphic and there was no significant deviation from the Hardy-Weinberg equilibrium (HWE) excepting